A study published in the August 29, 2014, issue of the Annals of Vertebral Subluxation Research documented the resolution of a case of a painful condition where there is hand numbness/tingling, weakness, clumsiness, coldness, and aching pain. Occasionally, headaches are experienced as well. This is known as "T4" syndrome. This condition is four times more common in women than men.

The study's authors explained that, "The T4 Syndrome involves unilateral or bilateral upper extremity pain and paresthesia originating from the upper thoracic spine. The onset is usually gradual and non-traumatic."

In this case, a 62-year-old woman had complaints of upper mid-back pain and bilateral hand numbness and tingling, mostly involving the 4th and 5th fingers. The hand problems were the most severe in the morning. The woman's symptoms began without warning about a week before seeking chiropractic care.

A physical and chiropractic examination was performed on the woman. Based on the examination, a determination was made that subluxations were present in the lower neck, and in the upper-mid back area of the spine. From these findings, chiropractic adjustments were started to address the subluxations.
By the fifth visit to the chiropractor, both her hand numbness and mid-back pain had been completely resolved.